Objectives : The purpose of this paper was to systematically review current researches about self-harm and suicide attempt in adolescents. Method: Keywords of “suicide attempt”, “nonsuicidal self-injury” (NSSI), “self-harm”, and “deliberate self-harm” (DSH) were searched through PsycINFO and PubMed. The SID and Mental Health Research Network (MHRN) databases were also searched for domestic resources. Of 120 collected English articles, and after eliminating the irrelevants, 30 articles were selected based on the study design, the sampling methods, and the goals of the study. The Persian articles were studied separately. Results: Suicide attempt could be predicted by severity of self-harm. There exists many common risk factors for self-harm and suicide attempt. Symptoms of depression, the frequency of posttraumatic stress disorder and borderline personality disorder in adolescents with history of suicide attempt are greater than that of adolescents with history of self-harm. Difficulties in regulating emotions and red uction of fear of death which are gained through repetition of self-harm were two factors explained relationship between self-harm and suicide attempt. Conclusion: It seems that the difference between self-harm and suicide attempt is quantitative, but reasons for self-harm was differ from suicide attempt .