Extended Abstract
1. Introduction
Anxiety disorders are a group of most common and disabling mental disorders in children and adolescents. More than 10% of this age category suffer from anxiety disorders during their development [1, 2]. Diagnostic and Statistical Manual of Mental Disorders–fifth edition (DSM-5) has separated Obsessive-Compulsive Disorder (OCD) from the category of anxiety disorders and considered it as a distinct category [5]. Genetic factors have significant importance in development and persistence of anxiety. Correlation between psychiatric disorders in parents and children has been a main research area in child psychopathology, but the direct impact of different mental disorders in mothers on their children is not clear and yet to be identified [13]. Theatrical models of anxiety disorders in children emphasized the mutual relationship between parent and child under stressful environment [15, 16]. This study aims to compare personality traits and psychopathology in three groups of mothers of children with Anxiety Disorders, Obsessive-Compulsive Disorder, and healthy group.
2. Method
This research was a cross-sectional descriptive study. Study population was mothers of children with Anxiety Disorders, Obsessive-Compulsive Disorder, and healthy group. Mothers were interviewed with Structured Clinical Interview for DSM Disorders (SCID-I) and completed NEO Five-Factor Inventory (NEO-FFI-60). Sample size of 93 mothers (35 in anxiety group, 27 in obsessive group and 31 in healthy group) were selected, using available sampling.
3. Results
According to Figure 1, 40% mothers of children with anxiety disorders were diagnosed with an anxiety disorder, 17.4% diagnosed with depression and 20% diagnosed with comorbid anxiety and depression. In mothers of children with Obsessive-Compulsive Disorder, 25.9% had diagnosis of anxiety, 14.8% obsession, 14.8% depression and 22.25% comorbid anxiety and depression. Finally, in mothers of children in normal healthy group, diagnosis rate of anxiety disorders and depression was 16.2% and 3.2%, respectively. 

Results of multivariate analysis of variance showed significant statistical difference in neuroticism, extraversion and openness to experience between three groups of mothers (Table 1). The value of Chi-Square and significance level of P<0.001 indicate that there is a prominent difference between three groups in psychopathology of mothers and mean scores of all the groups indicate that psychopathology of mothers of children with anxiety and obsession is more than healthy group significantly (Table 2).

4. Discussion 
Findings indicate that the mean scores of the healthy group in neuroticism trait were lesser than anxiety and obsession group and the mean scores of obsession group in extraversion and openness to experience traits was lesser than anxiety and healthy group. With regards to psychopathology of mothers, results indicate that there is no significant difference in anxiety and obsession group; however, psychopathology in these two groups was significantly greater than healthy group. Despite important role of genetic heritability in children anxiety, which explain a considerable amount (at least one third) of variance, effect mechanisms of that are yet to be identified properly [18, 28]. Explaining this findings, along with emphasis on the role of inheritance as a predisposing factor in development of anxiety and obsessive-compulsive disorders in children, potential role of parent psychopathology related mediator variables such as caregiver stress, family structure malfunction, parent’s emotional dysregulation towards the child, dysfunctional modeling and reinforcement of maladjusted strategies (e.g. avoidance) could be mentioned [31, 33]. Results of this study marked that considering parent’s psychopathology in prevention and treatment of anxiety and obsessive-compulsive disorders in children may be of great importance.
Ethical Considerations
Compliance with ethical guidelines
In this research all ethical considerations such as informed consent, preservation of anonymity and secrecy, voluntary participation in the interview and assessment were observed. The project was approved by research ethics committee of the Iran University of Medical Science.
Funding
This research was extracted from the research project with code 25440 that was financially supported by the Mental Health Research Center, Iran University of Medical Sciences, Tehran, Iran.
Conflict of interest
No conflict of interest is reported for any of the contributing authors. 
Acknowledgements 
In the end, we thank all the participants who helped us complete this study.

 

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