Psychosocial stresses, as one of the causative factors of mental and physical disorders, are considered to be important health issues. Thus, for identifying vulnerable groups, it is necessary to identify and evaluate these stressors. The purpose of this study is to review the relationship between stress and incidence of mental disorders and to quqntify this relationship and to compare psychiatric signs in different groups by using the Life Events Inventory and SCl-90-R questionnaires. 410 subjects (211 females, 199 males with a mean age of 31.3 years) participated in this study Subjects were selected from Zahedan general population through cluster random sampling. Data were analyzed using the Z test. Analysis of variance and the Turkey method were done using the SPSS package. Resylts showed that there was little difference between the sample mean (57.2) and the cut of point (58.3). It was also found that psychiatric problems were more severe and occurred more frequently among single, low educated individuals and women. Men, young people, and Balooches are confronted with more stressful events. The most common life stressors were hospitalization of a family member, birth of a new member in the family, unwxpected mortality, financial problems, inflation, unemployement and family discordes.