Objectives: The purpose of this study was to compare temperament-character dimensions of personality among patients with separation anxiety disorder and healthy person. Method: This research has Ex Post Facto Research Design. The sample consisted of 200 female students from Tehran and Shahed universities who were selected through convenient sampling method. The participants were assessed by the 27-item Adult Separation (ASA-27), the Structured Clinical Interview for Separation Anxiety Symptoms in Adults (SCI-SAS), and the Temperament and Character Inventory (TCI). Multivariate analysis of variance (MANOVA) was used for data analysis. Results: The results showed that, compared to healthy individuals, the group with adult separation anxiety obtained significantly higher scores on harm avoidance and reward dependence (p<0.001) and significantly lower scores on self-directedness (p<0.001) and cooperativeness (p<0.01). Conclusion: Temperament-character dimensions of personality play a significant role in intensifying and maintaining the clinical characteristics of adult separation anxiety disorder.
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