Objective : early school dropout and its social and behavioral consequences is one of the important problems among the students in particular at middle school level. In this study the psycho-social factors associated with school performance of middle school Shahed [1] students are examined in Hamedan province. Method: 889 Shahed students and 51 non-Shahed students from the same school were evaluated by survey method and through the following scales: Questionnaire developed by the researcher as educational attitude scale, Cooper-smith Self-Esteem Scale, and Children Depression Scale (CDS). Findings: the data analysis of this research was based on multivariate regression, indicates that from the variables associated with the research hypothesis, some factors such as family, self esteem, depression, level of satisfaction with mother, and the length of the father's absence, can explain the variation of students' average scores on school performance.