Objectives: The purpose of this research was to investigate the psychometric characteristics of Pain Self-Management Checklist (PSMC) in the population with chronic pain. Method: First, the checklist was administered to 186 patients with chronic pain, selected through random sampling in Tehran (n=86) and Ardebil (n=100). Then, test-retest reliability coefficient was evaluated with another 30 patients with chronic pain. In addition to the PSMC, some other checklists including Physical Disability Questionnaire (PDQ), Depression, Anxiety, Stress Scale (DASS-21), Multidimensional Pain Inventory (MPI), and chronic pain case-finding questionnaire were used for data collection. To validate the PSMC, its correlation with other instruments was investigated, and the reliability was calculated using Chronbach’s alpha and test-retest. Results: The results indicated that this checklist has high correlation with most important pain co-morbidity constructs (depression, anxiety, stress and physical disability). Therefore, it has appropriate construct validity. Moreover, the reliability of this checklist using Chronbach’s alpha and test-retest was appropriate. Conclusion: This study provides evidence for the advantage of using this checklist for Iranian patients.