Volume 11, Issue 2 (8-2005)                   IJPCP 2005, 11(2): 219-223 | Back to browse issues page

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1- , E-mail: mosavinm@sums.ac.ir
Abstract:   (11636 Views)


Introduction: To evaluate blood glucose and body weight in patients treated with clozapine and conventional antipsychotics.

Method: Forty-three patients with schizophrenia (36 males and 7 females) on clozapine were com- pared with 41 patients (33 males and 8 females) treated with conventional antipsychotics, regard-ing their fasting blood glucose (FBS), 2 hours post-prandial glucose (2HPPG) and body mass index (BMI). Data were analyzed using t-test and the chi-sqaure.

Results: Of the patients on clozapine, 2 had high FBS, 6 had high 2HPPG, and 5 were diagnosed with diabetes, which was significantly different from the group on conventional antipsychotics. More- over, comparing the BMIs, the patients on clozapine had higher weights than the conventional treatment group.

Conclusion: Clozapine may play a role in high blood glucose of some of the patients.

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Type of Study: Original Research | Subject: Psychiatry and Psychology
Received: 2007/02/19 | Published: 2005/08/15