Volume 1, Number 2 and 3 (Fall & Winter 1994)                   IJPCP 1994, 1(2 and 3): 14-20 | Back to browse issues page


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Shirazi M A. A Comparative Study on the Effectiveness of Three Psychotropic Drugs in the Treatment of Obsessive Compulsive Disorder. IJPCP. 1994; 1 (2 and 3) :14-20
URL: http://ijpcp.iums.ac.ir/article-1-1647-en.html

Psychiatrist Iran University of Medical Sciences
Abstract:   (8370 Views)

The guiding rationale for the present study stemmed from the observations pertaining to a relatively high prevalence of obsessive compulsive disorder in Iran and the importance of psychotropic drugs in the initial treatment and management of these cases. In this context, the aim of this investigation was to compare the relative efficacy of clomipramine, fluoxetine and tranylcypromine in the symptomatic treatment of this disorder. Over a span of 3 years (1991-1994). A total number of 150 subjects were treateed by either one of the above mentioned drugs. Results indicate that fluoxetine (followed by clomipramine) was more effective in terms of speed and quality of efficacy on obsessive and compulsive symptoms and produced relatively lesser adverse side effects than tranylcypromine. Tranylcypromine was not very effective in the tratement of obsessive compulsive symptoms.

Full-Text [PDF 3491 kb]   (1926 Downloads)    
Type of Study: Original Research | Subject: General
Received: 2012/12/2

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