fa کیفیت زندگی بیماران مبتلا به اختلال دوقطبی و برخی ویژگی‌های بالینی آنها روانپزشکی و روانشناسی Psychiatry and Psychology پژوهشي اصيل Original Research <p class="a0" dir="rtl" style="TEXT-JUSTIFY: kashida MARGIN: 0cm 0cm 0pt TEXT-INDENT: 0cm LINE-HEIGHT: 19pt TEXT-ALIGN: justify TEXT-KASHIDA: 0% mso-line-height-rule: exactly"><span lang="AR-SA" style="FONT-SIZE: 8pt FONT-FAMILY: Tahoma"><strong>چکیده<p></p></strong></span></p><p class="a" dir="rtl" style="MARGIN: 0cm 0cm 0pt LINE-HEIGHT: 19pt mso-line-height-rule: exactly"><strong><u><span lang="AR-SA" style="FONT-SIZE: 8pt FONT-STYLE: normal FONT-FAMILY: Tahoma">هدف</span></u><span lang="AR-SA" style="FONT-SIZE: 8pt FONT-STYLE: normal FONT-FAMILY: Tahoma">:</span></strong><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"><em> هدف پژوهش حاضر، بررسی کیفیت زندگی بیماران مبتلا به اختلال دوقطبی، در سه مقطع هنگام بستری، زمان ترخیص و شش ماه پس از آن در بیمارستان روزبه بود. </em></span><strong><u><span lang="AR-SA" style="FONT-SIZE: 8pt FONT-STYLE: normal FONT-FAMILY: Tahoma">روش</span></u><span lang="AR-SA" style="FONT-SIZE: 8pt FONT-STYLE: normal FONT-FAMILY: Tahoma">:</span></strong><em><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"> در این پژوهش 120 بیمار 18 تا 65 ساله مبتلا به اختلال دوقطبی نوع یک، در دوره مانیا یا مختلط، بستری در بیمارستان روزبه، به شکل پی‌درپی از اردیبهشت 1384 تا شهریور 1385 وارد بررسی شدند. داده‌ها به‌کمک پرسش‌نامه</span><span dir="ltr" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma">WHOQOL-BREF</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"><span dir="rtl"></span>، پرسش‌نامه افسردگی‌هامیلتون، مقیاس رتبه‌بندی مانیای یانگ، مقیاس علایم مثبت و منفی (</span><span dir="ltr" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma">PANSS</span><span dir="rtl"></span><span lang="FA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma mso-bidi-language: FA"><span dir="rtl"></span>)</span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma">، مقیاس ارزیابی کلی عملکرد (</span><span dir="ltr" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma">GAF</span><span dir="rtl"></span><span lang="FA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma mso-bidi-language: FA"><span dir="rtl"></span>)</span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"> و پرسش‌نامه رضایت مراجع در سه مقطع هنگام بستری، زمان ترخیص و شش ماه پس از آن بررسی شد. میزان بینش بیماران به‌کمک زیرمقیاس «بینش و قضاوت» پرسش‌نامه </span><span dir="ltr" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma">PANSS</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"><span dir="rtl"></span> ارزیابی گردید. </span></em><strong><u><span lang="AR-SA" style="FONT-SIZE: 8pt FONT-STYLE: normal FONT-FAMILY: Tahoma">یافته‌ها</span></u><span lang="AR-SA" style="FONT-SIZE: 8pt FONT-STYLE: normal FONT-FAMILY: Tahoma">:</span></strong><em><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"> کیفیت زندگی در زمان بستری و شش ماه پس از آن تفاوت معنی‌داری نداشت. بارزترین یافته، ارتباط معکوس علایم افسردگی با کیفیت زندگی، در زمان بستری (001/0</span><span dir="ltr" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma">p<</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"><span dir="rtl"></span>)، ترخیص (001/0</span><span dir="ltr" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma">p<</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"><span dir="rtl"></span>) و پی‌گیری شش ماه بعد (001/0</span><span dir="ltr" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma">p=</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"><span dir="rtl"></span>) بود</span><span dir="ltr"></span><span dir="ltr" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"><span dir="ltr"></span>.</span><span dir="rtl"></span><span style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"><span dir="rtl"></span> <span lang="AR-SA"><font size="2">علایم عمومی پسیکوز نیز در زمان بستری (001/0</font></span></span><span dir="ltr" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma">p<</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"><span dir="rtl"></span>)، ترخیص (01/0</span><span dir="ltr" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma">p<</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"><span dir="rtl"></span>)</span><span dir="ltr"></span><span lang="AR-SA" dir="ltr" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"><span dir="ltr"></span> </span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma">و شش ماه پس از بستری (001/0</span><span dir="ltr" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma">p<</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"><span dir="rtl"></span>)، ارتباطی معکوس با کیفیت زندگی نشان داد. علایم منفی پسیکوز، ارتباطی معنی‌دار و معکوس با کیفیت زندگی در هنگام بستری (005/0</span><span dir="ltr" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma">p<</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"><span dir="rtl"></span>) و ترخیص (05/0</span><span dir="ltr" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma">p<</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"><span dir="rtl"></span>) نشان دادند. </span></em><strong><u><span lang="AR-SA" style="FONT-SIZE: 8pt FONT-STYLE: normal FONT-FAMILY: Tahoma">نتیجه‌گیری</span></u><span lang="AR-SA" style="FONT-SIZE: 8pt FONT-STYLE: normal FONT-FAMILY: Tahoma">:</span></strong><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 8pt FONT-FAMILY: Tahoma"><em> کیفیت زندگی بیماران شش ماه پس از بستری در بیمارستان تغییر بارزی نمی‌کند. <p></p></em></span></p> <p class="MsoNormal" style="TEXT-JUSTIFY: kashida MARGIN: 0cm 0cm 0pt DIRECTION: ltr LINE-HEIGHT: 14.5pt unicode-bidi: embed TEXT-ALIGN: justify TEXT-KASHIDA: 0% mso-line-height-rule: exactly"><b><span style="FONT-SIZE: 10pt FONT-FAMILY: "Arial Black" mso-bidi-font-family: 'B Lotus'">Abstract<p></p></span></b></p><p class="MsoNormal" style="TEXT-JUSTIFY: kashida MARGIN: 0cm 0cm 0pt DIRECTION: ltr LINE-HEIGHT: 14.5pt unicode-bidi: embed TEXT-ALIGN: justify TEXT-KASHIDA: 0% mso-line-height-rule: exactly"><font face="Times New Roman"><b><u><span style="FONT-SIZE: 9pt mso-bidi-font-family: 'B Lotus'">Objectives</span></u></b><b><span style="FONT-SIZE: 9pt mso-bidi-font-family: 'B Lotus'">:</span></b><span style="FONT-SIZE: 9pt mso-bidi-font-family: 'B Lotus'"> The aim of the present study was to evaluate <span style="LETTER-SPACING: -0.2pt">the quality of life in a group of patients with bipolar disorder</span> <span style="LETTER-SPACING: -0.2pt">at admission, discharge and six month after hospitalization</span> in <placename w:st="on"><span style="LETTER-SPACING: -0.2pt">Roozbeh</span></placename><span style="LETTER-SPACING: -0.2pt"> <placetype w:st="on">Hospital</placetype>, <place w:st="on"><city w:st="on">Tehran</city>, <country-region w:st="on">Iran</country-region></place>. <b><u>Method</u>:</b> In a cohort study,</span> one hundred and twenty hospitalized patients with bipolar<span style="mso-spacerun: yes">  </span>disorder type I or mixed episode, aged between 18 and 65 years, were included in a consecutive manner from May, <span style="LETTER-SPACING: -0.2pt">2005 to September, 2006. Data were collected using World</span> <span style="LETTER-SPACING: -0.2pt">Health Organization-Quality of Life-Bref scale (WHO-QoL-</span>BREF), Young Mania Rating Scale (YMRS), Hamilton <span style="LETTER-SPACING: -0.2pt">Rating Scale for Depression-17 </span></span><span dir="rtl"></span></font><span lang="AR-SA" dir="rtl" style="FONT-SIZE: 9pt FONT-FAMILY: "B Lotus" LETTER-SPACING: -0.2pt"><span dir="rtl"></span>)</span><font face="Times New Roman"><span style="FONT-SIZE: 9pt LETTER-SPACING: -0.2pt mso-bidi-font-family: 'B Lotus'">HAM-D-17), Positive And</span><span style="FONT-SIZE: 9pt mso-bidi-font-family: 'B Lotus'"> Negative Symptom Scale (PANSS), Global Assessment <span style="LETTER-SPACING: -0.3pt">of Functioning (GAF), and Client Satisfaction Questionnaire</span> <span style="LETTER-SPACING: 0.4pt">(CSQ) at admission, discharge and six months after </span><span style="LETTER-SPACING: -0.3pt">hospitalization. <b><u>Results</u>:</b> Quality of life was not significantly</span> different between the time of admission and six months after hospitalization. The most significant finding was the reverse relationship between depressive symptoms and <span style="LETTER-SPACING: -0.2pt">quality of life at admission (p<0.001), discharge (p<0.001),</span> <span style="LETTER-SPACING: -0.2pt">and after six months follow-up (p=0.001). General psychotic</span> <span style="LETTER-SPACING: -0.2pt">symptoms also showed a reverse relationship at admission</span> <span style="LETTER-SPACING: 0.4pt">(p<0.001), discharge (p<0.01), and six months after </span>hospitalization (p<0.001). Negative psychotic symptoms showed a significant reverse relationship with quality of <span style="LETTER-SPACING: 0.4pt">life at admission (p<0.005) and discharge (p<0.05). </span><b><u><span style="LETTER-SPACING: -0.3pt">Conclusion</span></u><span style="LETTER-SPACING: -0.3pt">:</span></b><span style="LETTER-SPACING: -0.3pt"> Quality of life shows no significant improvement</span> six months after hospitalization. <p></p></span></font></p><p class="MsoNormal" style="TEXT-JUSTIFY: kashida MARGIN: 0cm 0cm 0pt DIRECTION: ltr LINE-HEIGHT: 14.5pt unicode-bidi: embed TEXT-ALIGN: justify TEXT-KASHIDA: 0% mso-line-height-rule: exactly"><font face="Times New Roman"><i><span style="FONT-SIZE: 9pt mso-bidi-font-family: 'B Lotus'"><p></p></span></i></font></p> اختلال دوقطبی؛ کیفیت زندگی؛ علایم پسیکوتیک bipolar disorder; quality of life; psychotic; symptoms 175 182 http://ijpcp.iums.ac.ir/browse.php?a_code=A-10-1-345&slc_lang=fa&sid=1 Homayoun Amini همایون امینی E-mail: aminihom@tums.ac.ir 180031947532846002916 180031947532846002916 Yes Zeinab Alimadadi زینب علی‌مددی 180031947532846002917 180031947532846002917 No Aliakbar Nejatisafa علی‌اکبر نجاتی‌صفا 180031947532846002918 180031947532846002918 No Vandad Sharifi ونداد شریفی 180031947532846002919 180031947532846002919 No Seyed Ali Ahmadi-Abhari سید علی احمدی ابهری 180031947532846002920 180031947532846002920 No