fa پی‌گیری یک‌ساله بیماران مبتلا به اختلال دوقطبی بستری‌شده در بیمارستان روزبه روانپزشکی و روانشناسی Psychiatry and Psychology پژوهشي اصيل Original Research <p class="MsoNormal" style="TEXT-JUSTIFY: kashida MARGIN: 0cm 0cm 0pt DIRECTION: ltr LINE-HEIGHT: 12pt unicode-bidi: embed TEXT-ALIGN: justify TEXT-KASHIDA: 0% mso-line-height-rule: exactly"><b><span style="FONT-SIZE: 10pt FONT-FAMILY: "Arial Black" mso-bidi-font-family: 'B Lotus'">Abstract<p></p></span></b></p><p class="MsoNormal" style="TEXT-JUSTIFY: kashida MARGIN: 0cm 0cm 0pt DIRECTION: ltr LINE-HEIGHT: 12pt unicode-bidi: embed TEXT-ALIGN: justify TEXT-KASHIDA: 0% mso-line-height-rule: exactly"><font face="Times New Roman"><b><u><span style="FONT-SIZE: 9pt mso-bidi-font-family: 'B Lotus'">Objectives</span></u></b><b><span style="FONT-SIZE: 9pt mso-bidi-font-family: 'B Lotus'">:</span></b><span style="FONT-SIZE: 9pt mso-bidi-font-family: 'B Lotus'"> The aim of this study was to evaluate the outcome of a group of<span style="mso-spacerun: yes">  </span>patients with bipolar I disorder admitted to Roozbeh Hospital, Tehran, Iran,<span style="mso-spacerun: yes">  </span>during one year follow up. <b><u>Method</u>:</b> In this prospective naturalistic study, 131 subjects with bipolar I disorder who were con-secutively admitted to the hospital were enrolled. Patients were assessed at baseline, discharge, and 6 and 12 months after admission to the hospital. Different aspects of response to treatment including severity of mood and psychotic symptoms, extrapyramidal side effects, global functioning and service satisfaction were assessed using a demographic questionnaire, Young Mania Rating Scale (Y-MRS), and Hamilton Rating Scale for Depression (HAM-D).<b> <u>Results</u>:</b> Severity of symptoms and function <span style="LETTER-SPACING: -0.3pt">showed significant improvement only at discharge (p<0.001),</span> and was not significant afterwards. Patients showed a <span style="LETTER-SPACING: -0.3pt">response rate of 65.4% based on 50% decrease on (Y-MRS),</span> at discharge. <b><u>Conclusion</u>:</b> Improvement in symptom <span style="LETTER-SPACING: -0.3pt">severity and global functioning was significant at discharge</span> but there was no significant improvement after discharge and during one year follow up.<p></p></span></font></p> اختلال دوقطبی؛ پیامد درمان؛ بررسی طولی bipolar disorder; treatment outcome; longitudinal study 168 174 http://ijpcp.iums.ac.ir/browse.php?a_code=A-10-1-344&slc_lang=fa&sid=1 Homayoun Amini همایون امینی 180031947532846002906 180031947532846002906 No Vandad Sharifi ونداد شریفی 180031947532846002907 180031947532846002907 No Aliakbar Nejatisafa علی‌اکبر نجاتی‌صفا 180031947532846002908 180031947532846002908 No Mohammad Arbabi محمد اربابی 180031947532846002909 180031947532846002909 No Maryam Tabatabaie مریم طباطبایی E-mail: tabatabaee@sina.tums.ac.ir 180031947532846002910 180031947532846002910 Yes Zeinab Alimadadi زینب علی‌مددی 180031947532846002911 180031947532846002911 No Farhad Faridhosseini فرهاد فریدحسینی 180031947532846002912 180031947532846002912 No Mahdi Rafiei Milajerdi مهدی رفیعی میلاجردی 180031947532846002913 180031947532846002913 No Alireza Manouchehri علیرضا منوچهری 180031947532846002914 180031947532846002914 No Arshia Seddige ارشیا صدیق 180031947532846002915 180031947532846002915 No