fa نقش جنسیت در سبب‌شناسی خانوادگی مبتلایان به اختلال بیش‌فعالی با کمبود توجه روانپزشکی و روانشناسی Psychiatry and Psychology پژوهشي اصيل Original Research   <p class="a0" dir="rtl" style="MARGIN-LEFT: 1cm TEXT-INDENT: 0cm" align="right"><a name="_Toc78619153"><span lang="AR-SA" style="FONT-SIZE: 20pt FONT-FAMILY: BTahoma"><font color="#cc0000" size="4">چکیده</font></span></a> </p><p class="a0" dir="rtl" style="MARGIN-LEFT: 1cm TEXT-INDENT: 0cm" align="right"> <span lang="AR-SA" style="FONT-SIZE: 10pt FONT-STYLE: normal FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><strong>هدف:</strong></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><font size="2"><span style="mso-spacerun: yes">  </span>این پژوهش با هدف بررسی نقش جنسیت در خطر ابتلا به اختلال بیش‌فعالی با کمبود توجه</font></span><span dir="ltr"></span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma"><span dir="ltr"></span>(ADHD)</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> در افراد خانواده مبتلایان به این اختلال انجام شده است.</span></p><p></p><p class="a" dir="rtl"><span lang="AR-SA" style="FONT-SIZE: 10pt FONT-STYLE: normal FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><strong>روش‌: </strong></span><font size="2"><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span style="mso-spacerun: yes"><strong> </strong></span></span><span lang="FA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-bidi-language: FA mso-ansi-font-size: 9.0pt">997 خویشاوند </span></font><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt">درجه یک (554 والد و 443 خواهر و برادر) 277 کودک و نوجوان مبتلا به </span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">ADHD</span><span dir="rtl"></span><span style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> <span lang="AR-SA"><font size="2">5 تا 17 ساله که به روش نمونه‌‌گیری در دسترس از میان مراجعان به درمانگاه روانپزشکی کودکان بیمارستان دکتر شیخ مشهد انتخاب شده بودند، ارزیابی شدند. تشخیص </font></span></span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">ADHD</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span><font size="2"><span style="mso-spacerun: yes">  </span>در بیماران با مصاحبه بالینی روانپزشک و آزمون تشخیصی </font></span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">K-SADS</span><span dir="rtl"></span><span style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> <span lang="AR-SA"><font size="2"><span style="mso-spacerun: yes"> </span>و بررسی وجود </font></span></span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">ADHD</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span><font size="2"><span style="mso-spacerun: yes">  </span>در افراد خانواده بیماران با استفاده از مصاحبه بالینی روانپزشکی و آزمون‌های تشخیصی </font></span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">K-SADS</span><span dir="rtl"></span><span style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> <span lang="AR-SA"><font size="2">و</font></span></span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">Wender</span><span dir="rtl"></span><span style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> <span lang="AR-SA"><font size="2"><span style="mso-spacerun: yes"> </span>انجام شد.</font></span></span></p><p></p><p class="a" dir="rtl"><span lang="AR-SA" style="FONT-SIZE: 10pt FONT-STYLE: normal FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><strong>یافته‌ها:</strong></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><strong> </strong>تفاوتی در میزان ابتلای افراد خانواده مبتلایان دختر و پسر </span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">ADHD</span><span dir="rtl"></span><span style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> <span lang="AR-SA"><font size="2">دیده نشد.</font></span></span></p><p></p><p class="a" dir="rtl"><span lang="AR-SA" style="FONT-SIZE: 10pt FONT-STYLE: normal FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><strong>نتیجه‌گیری:</strong></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><font size="2"><span style="mso-spacerun: yes"><strong>  </strong></span>این بررسی نشان داد که جنسیت یک عامل خطر ژنتیک- خانوادگی برای ابتلا به </font></span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">ADHD</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> و تجمع خانوادگی </span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">ADHD</span><span dir="rtl"></span><span style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> <span lang="AR-SA"><font size="2">به‌شمار نمی‌رود.</font></span></span></p><p></p><p class="a" dir="rtl"><span lang="AR-SA" style="FONT-SIZE: 20pt FONT-FAMILY: BTahoma"></span></p><p align="right" ><p class="a" dir="rtl" align="right"><span style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: BTahoma mso-ansi-font-size: 9.0pt"><span lang="AR-SA"><font face="BTahoma" size="2"></font></span></span> </p>  <p class="MsoNormal" style="TEXT-JUSTIFY: kashida DIRECTION: ltr TEXT-INDENT: 0cm LINE-HEIGHT: 15pt MARGIN-RIGHT: 6.5pt unicode-bidi: embed TEXT-ALIGN: justify TEXT-KASHIDA: 0% mso-line-height-rule: exactly"><b><span style="FONT-SIZE: 10pt FONT-FAMILY: "><font color="#cc0000">Abstract</font></span></b></p><p></p><p class="MsoNormal" style="TEXT-JUSTIFY: kashida DIRECTION: ltr TEXT-INDENT: 0cm LINE-HEIGHT: 15pt MARGIN-RIGHT: 6.5pt unicode-bidi: embed TEXT-ALIGN: justify TEXT-KASHIDA: 0% mso-line-height-rule: exactly"><b><span style="FONT-SIZE: 10pt LETTER-SPACING: -0.2pt mso-bidi-font-family: 'B Lotus'">Objectives: </span></b><span style="FONT-SIZE: 10pt LETTER-SPACING: -0.2pt mso-bidi-font-family: 'B Lotus'">The aim of this study was to assess the influence of gender</span><span style="FONT-SIZE: 10pt mso-bidi-font-family: 'B Lotus'"> on familial transmission of attention deficit hyperactivity disorder (ADHD).</span></p><p></p><p class="MsoNormal" style="TEXT-JUSTIFY: kashida DIRECTION: ltr TEXT-INDENT: 0cm LINE-HEIGHT: 15pt MARGIN-RIGHT: 6.5pt unicode-bidi: embed TEXT-ALIGN: justify TEXT-KASHIDA: 0% mso-line-height-rule: exactly"><b><span style="FONT-SIZE: 10pt mso-bidi-font-family: 'B Lotus'">Method: </span></b><span style="FONT-SIZE: 10pt mso-bidi-font-family: 'B Lotus'">997 first degree relatives (554 parents, 443 siblings) of 277 probands with ADHD (aged 5-17 yrs) who were selected using con-venience sampling from among patients referred to the clinic of child psychiatry at Dr. Sheikh Hospital in the city of </span><city /><p lace ><span style="FONT-SIZE: 10pt mso-bidi-font-family: 'B Lotus'">Mashad</span></place /></city /><span style="FONT-SIZE: 10pt mso-bidi-font-family: 'B Lotus'">, were studied. The diagnosis of ADHD for patients was made by clinical interview <font size="2"><span style="LETTER-SPACING: -0.25pt">by a psychiatrist and Kiddie-Scheduale for Affective Disorders & Schizo-</span> phrenia (K-SADS), and screening for the presence of ADHD in the family members of the probands was done by psychiatric clinical interview as well as K-SADS and Wender diagnostic tests.</font></span></p><p></p><p class="MsoNormal" style="TEXT-JUSTIFY: kashida DIRECTION: ltr TEXT-INDENT: 0cm LINE-HEIGHT: 15pt MARGIN-RIGHT: 6.5pt unicode-bidi: embed TEXT-ALIGN: justify TEXT-KASHIDA: 0% mso-line-height-rule: exactly"><b><span style="FONT-SIZE: 10pt LETTER-SPACING: -0.1pt mso-bidi-font-family: 'B Lotus'">Results: </span></b><span style="FONT-SIZE: 10pt LETTER-SPACING: -0.1pt mso-bidi-font-family: 'B Lotus'">Our findings showed no gender differences in the prevalence</span><span style="FONT-SIZE: 10pt mso-bidi-font-family: 'B Lotus'"> of ADHD in the relatives of girls and boys with ADHD.</span></p><p></p><b><span style="FONT-SIZE: 10pt FONT-FAMILY: ">Conclusion: </span></b><span style="FONT-SIZE: 10pt FONT-FAMILY: ">This study showed that gender is not a genetic-familial <span style="LETTER-SPACING: -0.2pt"><font size="2">risk factor for developing ADHD and the familial aggregation of ADHD.</font></span></span> کلیدواژه: اختلال بیش‌فعالی با کمبود توجه، جنس، وراثت Key words: attention deficit hyperactivity disorder, gender, heredity 204 208 http://ijpcp.iums.ac.ir/browse.php?a_code=A-10-1-3&slc_lang=fa&sid=1 Paria Hebrani پریا حبرانی E-mail: phebrani@yahoo.com 1800319475328460048 1800319475328460048 Yes Javad Alaghbandrad جواد علاقبندراد 1800319475328460049 1800319475328460049 No Fariba Arabgol فریبا عربگل 1800319475328460050 1800319475328460050 No Mansour Salehi منصور صالحی 1800319475328460051 1800319475328460051 No Monavar Afzalaghaie منور افضل‌آقایی 1800319475328460052 1800319475328460052 No