fa آیا اختلال بیش‌فعالی با کمبود توجه در ویژگی‌های بالینی مانیای کودکان و نوجوانان مؤثر است؟ روانپزشکی و روانشناسی Psychiatry and Psychology پژوهشي اصيل Original Research <p><font style="BACKGROUND-COLOR: #f2fbf7" face="BTahoma" size="2"></font> </p><p class="a0" dir="rtl" style="MARGIN-LEFT: 1cm TEXT-INDENT: 0cm"><a name="_Toc78619153"><span lang="AR-SA" style="FONT-SIZE: 20pt FONT-FAMILY: BTahoma"><font color="#990000" size="4"><strong>چکیده</strong></font></span></a> </p><p class="a0" dir="rtl" style="MARGIN-LEFT: 1cm DIRECTION: rtl TEXT-INDENT: 0cm" align="justify" ><p class="a" dir="rtl"><span lang="AR-SA" style="FONT-SIZE: 10pt FONT-STYLE: normal FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><strong>هدف:</strong></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><strong> </strong>این بررسی با هدف تعیین اثرات همبودی با اختلال بیش‌فعالی با کمبود توجه</span><span dir="ltr"></span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma"><span dir="ltr"></span>(ADHD)</span><span dir="rtl"></span><span style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> <span lang="AR-SA"><font size="2">بر ویژگی‌های بالینی اختلال دوقطبی </font></span></span><span dir="ltr"></span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma"><span dir="ltr"></span>(BPD)</span><span dir="rtl"></span><span style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> <span lang="AR-SA"><font size="2">در کودکان و نوجوانان بستری در بیمارستان، انجام شد.</font></span></span></p><p></p><p class="a" dir="rtl"><span lang="AR-SA" style="FONT-SIZE: 10pt FONT-STYLE: normal FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><strong>روش‌: </strong></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt">ویژگی‌های بالینی 20 کودک و نوجوان 18-6 ساله مبتلا به </span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">BPD</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span>، بر پایه مصاحبه تشخیصی </span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">K-SADS</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> و تشخیص بالینی دو روانپزشک کودک و نوجوان، در دو گروه با و بدون </span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">ADHD</span><span dir="rtl"></span><span style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> <font size="2"><span style="mso-spacerun: yes"> </span><span lang="AR-SA">ارزیابی و مقایسه شد.</span></font></span></p><p></p><p class="a" dir="rtl"><span lang="AR-SA" style="FONT-SIZE: 10pt FONT-STYLE: normal FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><strong>یافته‌ها:</strong></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><strong> </strong>35% بیماران سابقه</span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">ADHD</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> داشتند. بروز</span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">BPD</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> در گروه</span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">BPD+ADHD</span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> زودرس‌تر بود. میزان اختلال‌های همبود نیز در این گروه بالاتر از گروه </span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">BPD </span><span dir="rtl"></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span><font size="2"><span style="mso-spacerun: yes"> </span>خالص بود.</font></span></p><p></p><p class="a" dir="rtl"><span lang="AR-SA" style="FONT-SIZE: 10pt FONT-STYLE: normal FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><strong>نتیجه‌گیری: </strong></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt">به نظر می‌رسد افراد مبتلا به</span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">BPD+ADHD</span><span dir="rtl"></span><span style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> <font size="2"><span style="mso-spacerun: yes"> </span><span lang="AR-SA">گروه ویژه‌ای از بیماران دو قطبی هستند؛ در این گروه بیماری‌های همراه فراوان‌تر، سن بروز مانیا پایین‌تر و چگونگی شروع بیماری بیشتر به شکل تحت حاد می‌باشد. بنابراین ممکن است </span></font></span><span dir="ltr" style="FONT-WEIGHT: normal FONT-FAMILY: Tahoma">ADHD</span><span dir="rtl"></span><span style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: Tahoma mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> <font size="2"><span style="mso-spacerun: yes"> </span><span lang="AR-SA">پیش ‌درآمد اختلال دو قطبی در کودکان و نوجوانان باشد.</span></font></span><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: "> </span></p><p></p><p class="a" dir="rtl"><span lang="AR-SA" style="FONT-WEIGHT: normal FONT-SIZE: 10pt FONT-FAMILY: "></span></p><p></p>  <p class="MsoNormal" style="TEXT-JUSTIFY: kashida DIRECTION: ltr TEXT-INDENT: 0cm LINE-HEIGHT: 15pt MARGIN-RIGHT: 6.5pt unicode-bidi: embed TEXT-ALIGN: justify TEXT-KASHIDA: 0% mso-line-height-rule: exactly"><b><span style="FONT-SIZE: 10pt FONT-FAMILY: "><font color="#cc0000">Abstract</font></span></b></p><p></p><p class="MsoNormal" style="TEXT-JUSTIFY: kashida DIRECTION: ltr TEXT-INDENT: 0cm LINE-HEIGHT: 15pt MARGIN-RIGHT: 6.5pt unicode-bidi: embed TEXT-ALIGN: justify TEXT-KASHIDA: 0% mso-line-height-rule: exactly"><b><span style="FONT-SIZE: 10pt mso-bidi-font-family: 'B Lotus'">Objectives: </span></b><span style="FONT-SIZE: 10pt mso-bidi-font-family: 'B Lotus'">To assess the impact of attention deficit hyperactivity <font size="2"><span style="LETTER-SPACING: -0.1pt">disorder (ADHD) on clinical characteristics of bipolar disorder (BPD)</span> in hospitalized children and adolescents. </font></span></p><p></p><p class="MsoNormal" style="TEXT-JUSTIFY: kashida DIRECTION: ltr TEXT-INDENT: 0cm LINE-HEIGHT: 15pt MARGIN-RIGHT: 6.5pt unicode-bidi: embed TEXT-ALIGN: justify TEXT-KASHIDA: 0% mso-line-height-rule: exactly"><b><span style="FONT-SIZE: 10pt LETTER-SPACING: -0.2pt mso-bidi-font-family: 'B Lotus'">Method: </span></b><span style="FONT-SIZE: 10pt LETTER-SPACING: -0.2pt mso-bidi-font-family: 'B Lotus'">Clinical characteristics of twenty 6-18 years old children and </span><span style="FONT-SIZE: 10pt mso-bidi-font-family: 'B Lotus'">adolescents with BPD was assessed and compared in two groups of <font size="2"><span style="LETTER-SPACING: -0.2pt">patients with or without ADHD, using K-SADS clinical interview and </span>the clinical diagnosis of two child and adolescent psychiatrists. </font></span></p><p></p><p class="MsoNormal" style="TEXT-JUSTIFY: kashida DIRECTION: ltr TEXT-INDENT: 0cm LINE-HEIGHT: 15pt MARGIN-RIGHT: 6.5pt unicode-bidi: embed TEXT-ALIGN: justify TEXT-KASHIDA: 0% mso-line-height-rule: exactly"><b><span style="FONT-SIZE: 10pt LETTER-SPACING: -0.2pt mso-bidi-font-family: 'B Lotus'">Results: </span></b><span style="FONT-SIZE: 10pt LETTER-SPACING: -0.2pt mso-bidi-font-family: 'B Lotus'">35% of patients had a history of ADHD. The onset of BPD in </span><span style="FONT-SIZE: 10pt LETTER-SPACING: -0.25pt mso-bidi-font-family: 'B Lotus'">the BPD+ADHD group was earlier. Comorbidity rates of other disorders </span><span style="FONT-SIZE: 10pt mso-bidi-font-family: 'B Lotus'">were also higher in this group than in the group with pure ADHD. </span></p><p></p><b><span style="FONT-SIZE: 10pt FONT-FAMILY: ">Conclusion: </span></b><span style="FONT-SIZE: 10pt FONT-FAMILY: ">It is likely that subjects with BPD+ADHD comprise a particular subgroup of bipolar patients. In this subgroup there is a higher rate of comorbidity and a lower age of mania onset the onset <font size="2"><span style="LETTER-SPACING: -0.2pt">of the disorder is also usually of subacute type. Therefore, ADHD may</span> be a harbinger of bipolar disorder in these children and adolescents.</font></span> کلیدواژه: اختلال دوقطبی، مانیا، اختلال بیش‌فعالی با کمبود توجه، کودکان، نوجوانان Key words: bipolar disorder, children, adolescents, ADHD 197 203 http://ijpcp.iums.ac.ir/browse.php?a_code=A-10-1-2&slc_lang=fa&sid=1 Zahra Shahrivar زهرا شهریور E-mail: sharivar@tums.ac.ir 1800319475328460045 1800319475328460045 Yes Javad Alaghbandrad جواد علاقبندراد 1800319475328460046 1800319475328460046 No Elham Shirazi الهام شیرازی 1800319475328460047 1800319475328460047 No