Shiva Soraya, Ruohollah Seddigh, Fatemeh Hadi, Mohammad Faramarzi,
Volume 28, Issue 1 (4-2022)
Abstract
Synthetic cannabinoids (SC) are a heterogeneous group of substances with a high affinity for cannabinoid receptors. Unlike Δ9-tetrahydrocannabinol (THC), synthetic cannabinoids are incredibly potent, highly productive, have more affinity for the cannabinoid receptor type 1 (CB1), and cannabinoid receptor type 2 (CB2), and are designed to accelerate the effects of tetrahydrocannabinol. Also, there is experimental evidence that SCs act on non-cannabinoid receptors, such as the 5-HT2B receptor or dopaminergic receptors.