Objectives : The current research aim was to consider the childhood traumas’ relationship with depression and suicide attempt in adulthood. Method: This study population consisted of all refereed individual to Loghman Hakim Hospital due to suicide attempt at the Fall 2011 and Winter 2012. Of these 180 people (100 females and 80 males) were selected by random sampling method and studied by inclusion-exclusion criteria. Also, 180 patients (100 females and 80 males) hospitalized during the Fall 2011 and Winter 2012 due to physical disease-without even indirect relevance with suicide- were examined. Data collection was by Beck Depression Inventory (BDI-II) and Childhood Trauma Questionnaire (CTQ). The data were analyzed using discriminant functions and multivariable regression. Results: By increasing the level of childhood traumas (all subscales) the suicide attempt probability (p≤0.001) was increased (p≤0.01). Of childhood trauma the emotional abuse had the most effect on suicide attempt. Moreover, there were relationships among emotional abuse (p≤0.01), physical neglect (p≤0.001) and emotional neglect (p≤0.001). Conclusion: Childhood traumas, especially emotional abuse may lead to depression and suicide attempt in adulthood .