Iranian Journal of Psychiatry and Clinical Psychology
مجله روانپزشكي و روانشناسي باليني ايران
IJPCP
Medical Sciences
http://ijpcp.iums.ac.ir
18
journal18
1735-4315
2228-7515
10.32598/ijpcp
fa
jalali
1384
11
1
gregorian
2006
2
1
11
4
online
1
fulltext
fa
مقایسه اثر کلوزاپین و ضدپسیکوزهای کلاسیک بر فشار و سلامت روانی مراقبان بیماران مبتلا به اسکیزوفرنیا
Comparison of the Effects of Clozapine and Conventional Antipsychotics on the Burden and Psychological Well-being of Caregivers of Patients with Schizophrenia
روانپزشکی و روانشناسی
Psychiatry and Psychology
پژوهشي اصيل
Original Research
<!--stripped--><b><span style="FONT-SIZE: 14pt">Abstract<p></p></span></b></p><p class="StyleBold" style="TEXT-JUSTIFY: kashida TEXT-ALIGN: justify TEXT-KASHIDA: 0%"><b>Introduction: </b>Due to the effect of symptoms of patients with schizophrenia on the psycholo-<span style="LETTER-SPACING: -0.25pt">gical well-being of their caregivers, this study was carried out to assess the effect of treatment with</span> clozapine and conventional antipsychotics on the caregivers’ burden and well-being. </p><p class="StyleBold" style="TEXT-JUSTIFY: kashida TEXT-ALIGN: justify TEXT-KASHIDA: 0%"><b><span style="LETTER-SPACING: -0.2pt">Method: </span></b><span style="LETTER-SPACING: -0.2pt">Two hundred and three patients with schizophrenia and their caregivers were examined</span> <span style="LETTER-SPACING: -0.1pt">in a retrospective study. The subjects were enrolled using the sequential method. Family Burden</span> <span style="LETTER-SPACING: -0.2pt">Interview Scale (FBIS), Morning-side Rehabilitation Status Scale (MRSS), General Health Ques-</span> <span style="LETTER-SPACING: -0.2pt">tionnaire (GHQ) and a demographic questionnaire were the instruments of this study. Chi-square,</span> correlation coefficient, multiple linear regression and t-student tests were used for data ana-lysis. </p><p class="StyleBold" style="TEXT-JUSTIFY: kashida TEXT-ALIGN: justify TEXT-KASHIDA: 0%"><b>Results: </b>The results showed that most patients treated with clozapine consisted of young un-employed men with a higher frequency of hospitalization and higher level of education. The <span style="LETTER-SPACING: -0.2pt">caregivers consisted mainly of parents. A positive correlation was observed between burden, psy-</span> <span style="LETTER-SPACING: -0.2pt">chological well-being and psychiatric symptoms of the patients. Psychiatric symptoms in general</span> <span style="LETTER-SPACING: -0.1pt">and negative symptoms in particular were less severe in the clozapine receiving group, but there</span> was no significant difference with regard to burden and well being among the caregivers. </p><p class="StyleBold" style="TEXT-JUSTIFY: kashida TEXT-ALIGN: justify TEXT-KASHIDA: 0%"><b><span style="LETTER-SPACING: -0.2pt">Conclusion: </span></b><span style="LETTER-SPACING: -0.2pt">By a better control of positive and negative symptoms in schizophrenia, clozapine</span> could possibly be effective in reducing burden and maintaining psychological well-being. </p>
کلیدواژه: اسکیزوفرنیا, مراقب, سلامت روانی, فشار روانی, ضدپسیکوز
Keywords: schizophrenia, caregiver, psychological well-being, burden, antipsychotic
396
406
http://ijpcp.iums.ac.ir/browse.php?a_code=A-10-1-44&slc_lang=fa&sid=1
K.
Malakouti
کاظم
ملکوتی
E-mail: malakouti@hbi.ir
18003194753284600181
18003194753284600181
Yes
M.
Poshtmashadi
مرجان
پشت مشهدی
18003194753284600182
18003194753284600182
No