@ARTICLE{Khosropoor, author = {Khosropoor, M. and Ashkani, H. and }, title = {Comparison of Latent Inhibition Mechanisms before and after Drug Therapy in Patients with Schizophrenia}, volume = {11}, number = {1}, abstract ={ Abstract Introduction: This study was aimed to compare the latent inhibition mechanisms (LI) in patients at the acute phase of schizophrenia with the patients whose symptoms were controlled by antipsy- chotic medications.Method: LI was evaluated using visual and auditory stimuli in three groups: The first group (n=30) included the patients at the acute psychotic phase that did not take any medication. The second group (n=35) were the patients whose symptoms were controlled by antipsychotic drugs. The third group (n=31) were normal controls with no history of schizophrenia. The error score in learning in the testing phase was regarded as a dependent variable.Results: The error scores in schizophrenia patients (acute phase and stable patients) were signifi-cantly higher as compared to the control group. The expected effect of LI was not observed in stable schizophrenia patients. Conclusion: Our results did not show an association between LI and the phases of schizophrenia. It seems that patient's unfamiliarity with the testing technology has influenced the findings.   }, URL = {http://ijpcp.iums.ac.ir/article-1-81-en.html}, eprint = {http://ijpcp.iums.ac.ir/article-1-81-en.pdf}, journal = {Iranian Journal of Psychiatry and Clinical Psychology}, doi = {}, year = {2005} }