%0 Journal Article %A Amini, Homayoun %A Rahimi- Nejad, Fatemeh %A Noroozian, Maryam %A Sharifi, Vandad %A Shakiba, Majid %T Neurological Soft Signs in Patients with First Episode Psychosis, their First-Degree Relatives and Healthy Controls %J Iranian Journal of Psychiatry and Clinical Psychology %V 13 %N 2 %U http://ijpcp.iums.ac.ir/article-1-157-en.html %R %D 2007 %K first-episode psychosis, neurological soft sings, schizophrenia, %X     Abstract   Objectives: This study aimed to evaluate and compare neurological soft signs (NSS) in patients with first episode psychosis, in their first-degree relatives, and in healthy control subjects.   Method: Thirty patients with first-episode psychosis, 30 of their first-degree relatives, and 30 healthy controls were evaluated by the Structured Clinical Interview for DSM-IV (SCID) for psychiatric assessment. Neurological Evaluation Scale (NES) was used for the evaluation of NSS, and Edinburgh Handedness Inventory (EHI) for laterality assessment. Data were analyzed by the following statistical tests: Chi-square, t-test, Fisher’s Exact Test, Kolmogorov-Smirnov Test, and non-parametric tests of Kruskal-Wallis and Mann-Whitney.   Results: First-episode psychotic patients had significantly higher NES total scores than the first-degree relatives, and the control group. On “sequencing of complex motor acts”, “motor coordination”, and “sensory integration” subscales of the NES, patients had significantly higher scores than the controls (respective p-values of %> http://ijpcp.iums.ac.ir/article-1-157-en.pdf %P 89-96 %& 89 %! Neurological Soft Signs in Patients with First Episode Psychosis, their First-Degree Relatives and Healthy Controls %9 Original Research %L A-10-1-157 %+ %G eng %@ 1735-4315 %[ 2007