Volume 11, Issue 1 (5-2005)                   IJPCP 2005, 11(1): 15-23 | Back to browse issues page

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Shirazi E, Tavakkolian R, Shahrivar Z. The Effects of Fluoxetine on Attention-Deficit Hyperactivity Disorder (ADHD): A Pilot Study. IJPCP. 2005; 11 (1) :15-23
URL: http://ijpcp.iums.ac.ir/article-1-80-en.html
1- , E-mail: Shirazi_elham@yahoo.com
Abstract:   (17153 Views)


Introduction: This study was aimed to determine the efficacy of fluoxetine in treating attention-deficit hyperactivity disorder (ADHD) in children and adolescents.

Method: Twenty-two children and adolescents (6-16 years) diagnosed as having ADHD (excluding mental retardation, comorbid disorders, using concomitant medications) based on clinical psychi-atric evaluation, Diagnostic Interview for Children and Adolescents (DICA), and Diagnostic and Statistical Manual of Mental Disorders-4th Edition (DSM-IV) were enrolled in an open clinical trial in a Child and Adolescent Psychiatric Clinic, 2000-2001. Fluoxetine was prescribed 20 mg a day for 7 weeks. The efficacy was assessed before and after treatment by means of three outcome mea- sures: Children Global Assessment Scale (CGAS), Conner's Parent Rating Scale (CPRS), Conners's Teacher Rating Scale (CTRS). The side effects were assessed using a questionnaire.

Results: Moderate to robust improvement (improvement >50%) were seen in 65%. Eighty-six percent reported no side effects. Mild to moderate side effects were experienced by 14% which dimi- nished with continuation of the medication.

Conclusion: Fluoxetine is well tolerated in children and adolescents and may be an alternative me- dication in ADHD patients who cannot take other medications.

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Type of Study: Original Research | Subject: Psychiatry and Psychology
Received: 2007/03/25 | Accepted: 2014/01/7 | Published: 2014/01/7

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