Volume 8, Issue 4 (5-2003)                   IJPCP 2003, 8(4): 11-15 | Back to browse issues page

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Khazaie H, Habibi F, Pourafkari N. The Effect of Fluphenazine Decanoate Every 2 WeeksVersus 6 Weeks in the Treatment of Schizophrenia and Schizoaffective Disorders. IJPCP. 2003; 8 (4) :11-15
URL: http://ijpcp.iums.ac.ir/article-1-211-en.html
Abstract:   (16262 Views)

Abstract

Objectives: To reduce risks and still take advantage of the benefits of the medication, the pur-pose of this study was to investigate the possible application of longer intervals between inje-ctions of fluphenazine deconoate intramuscularly in treatment of schizophrenia and schizo-affective disorders.

Method: In this double blind study, fifty patients with schizophrenia or schizoaffective dis-orders were randomly assigned to two groups of 25 patients. The first group received 25mg of fluphenazine decanoate every 2 weeks the second group was treated every 6 weeks. The two groups were then evaluated by CGI, Quality of Life Scale, Level of Functioning Scale, BPRS, and Maryland Psychiatric Research Center Involuntary MovementScale. Research data were analyzed by Chi-square and one-way analysis variance.

Findings: The findings did not support a clear difference in relapse symptoms and side effects.

Results: The use of injections of fluphenazine every 6 weeks instead of every 2 weeks in-creases the rate of patient compliance with treatment and also remarkably decreases side effects of antipsychotic drugs without increasing relapse symptoms. 

 

 

Full-Text [PDF 132 kb]   (2260 Downloads)    
Type of Study: Original Research | Subject: General
Received: 2007/10/29

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