Volume 18, Issue 2 (Summer 2012)                   IJPCP 2012, 18(2): 128-137 | Back to browse issues page

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Molavi P, Shahrivar Z, Mahmoodi Gharaee J, Basharpoor S, Sharghi A, Nikparvar F. Short-time Outcome Predictors of Bipolar Disorder Type I in Children and Adolescents . IJPCP. 2012; 18 (2) :128-137
URL: http://ijpcp.iums.ac.ir/article-1-1611-en.html
1- Ardabil University of Medical Sciences, Ardabil, Iran
2- Roozbeh Hospital, Tehran University of Medical Sciences , sharivar@sina.tums.ac.ir
3- Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran
4- University of Mohaghegh Ardebili, Iran University of Mohaghegh Ardebili, Iran
5- hahid Beheshti University, Tehran, Iran hahid Beheshti University, Tehran, Iran
Abstract:   (7672 Views)

Objectives: This study aimed to evaluate the three and six month clinical and demographic outcome predictors (recurrence rate, the rate of hospitalization, severity of illness and recovery rates) in a group of children and adolescents with type I bipolar disorders. Method: The participants of this longitudinal and prospective study were 80 children and adolescents admitted in Roozbeh Hospital, Tehran, Iran with a diagnosis of type I bipolar disorder. Consecutive referrals were included in a prospective cohort. The participants were evaluated at admission, discharge, and follow-up at 3 and 6 months, using demographic questionnaire, Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version-Persian Version (K-SADS-PL-PV), Young Mania Rating Scale (Y-MRS), Children Depression Inventory (CDI), Beck Depression Inventory (BDI), and Clinical Global Impression (CGI). The Pearson correlation coefficient and multivariate regressions were used for data analysis. Results: The 6-month follow-up showed that there was a positive correlation between the severity of mania with male gender (p=0.01) and the severity of mania at admission (p=0.04). The rate of recurrence at the 6-month follow-up was correlated (p=0.05, r=0.22) with psychosis at admission. The duration of untreated disorder (p=0.03) had a positive correlation with the severity of global impairment at the 6 month follow-up. Conclusion: This study confirms the role of some demographic and clinical features in predicting the course of disease and response to treatment. 

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Type of Study: Original Research | Subject: General
Received: 2012/10/31

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